{"id":339,"date":"2018-07-06T07:00:47","date_gmt":"2018-07-06T07:00:47","guid":{"rendered":"http:\/\/sweethoneybeehealth.com\/cbd\/?p=339"},"modified":"2018-07-07T01:58:16","modified_gmt":"2018-07-07T01:58:16","slug":"what-makes-cbd-so-effective-against-anxiety","status":"publish","type":"post","link":"http:\/\/sweethoneybeehealth.com\/cbd\/2018\/07\/06\/what-makes-cbd-so-effective-against-anxiety\/","title":{"rendered":"What makes CBD so effective against anxiety?"},"content":{"rendered":"

By a featured author from cbdvapejuice.net<\/a><\/p>\n

 <\/p>\n

Anxiety is an intensely irritating mental disorder that, if allowed to manifest, can have a debilitating effect on quality of life. Pernicious self-doubt creeps in and the stomach begins to turn, making the simplest of tasks a mighty ordeal as fears of embarrassment and humiliation kick in for no good reason. Anxiety can be a vicious circle \u2013 ceding to irrational worry often reinforces these doubts and, coupled with low self-esteem, we can end up becoming our own worst enemy. How can we go about life when we are constantly battling against ourselves?<\/p>\n

Thankfully, non-psychoactive cannabis, namely cannabidiol (CBD), is coming to the rescue of many anxiety patients around the world, many of whom consume the compound as part of a CBD vape oil<\/a>. This compound, which researchers have paid increasing interest to since the turn of the century, boasts anti-anxiety and antidepressant properties, which have been scientifically proven in both animal models and humans.<\/p>\n

CBD is a non-aggressive form of treatment, \u2013 the absence of tetrahydrocannabinol (THC) means there\u2019s no psychotropic side effects (i.e. getting high), and nor will CBD e-liquid<\/a>\u00a0have a numbing effect on your personality, as some medication is known to do.<\/p>\n

But what makes CBD so effective against anxiety? To understand this, we must first get to grips with the mechanism that CBD \u2013 along with other cannabinoids \u2013 functions in: the endocannabinoid system.<\/p>\n

CBD and the endocannabinoid system<\/h2>\n

In the early 1990s, researchers stumbled across a previously unknown network of neurotransmitters and receptors, which were found to hold influence over many physical and mental variables. The system typically works with endogenously-produced chemicals known as endocannabinoids, however, cannabinoids from cannabis are effective substitutes.<\/p>\n

For example, psychoactive THC bears many molecular similarities to anandamide, an important endocannabinoid which is a natural anti-depressant. Anandamide is called the \u2018human THC\u2019 or \u2018bliss molecule\u2019 by some and connects to CB1 receptors \u2013 these are highly-concentrated in the brain, which provides an explanation for THC\u2019s mind-altering effects.<\/p>\n

CBD also has an impact on anandamide, albeit a slightly more nuanced one. Instead of replacing the endocannabinoid, CBD helps to boost anandamide in the body by stopping the fatty acid amide hydrolase (FAAH) enzyme from breaking it down. Increased levels of anandamide in the body is likely to improve mood.<\/p>\n

However, CBD\u2019s benefits do not stop there \u2013 for anxiety, specifically, the interactions the compound has with gamma-Aminobutyric acid (GABA) neurons appear key. GABA is a neurotransmitter that, when operating correctly, has a calming effect on neuronal activity \u2013 an over-excited brain can cause all kinds of problems, including insomnia, schizophrenia, epilepsy and anxiety.<\/p>\n

CBD has a modulating effect on GABA, but curiously does not bind directly to CB1 <\/sub>or CB2 <\/sub>receptors. However, scientists have a good idea on how CBD interacts with GABA \u2013 and therefore reduces anxiety \u2013 from the effects endocannabinoids have on the neurotransmitter. When required, neurons can synthesize anandamide and 2-AG \u2013 research has shown that these endocannabinoids can directly influence GABA receptors.<\/p>\n

Public speaking study shows CBD outperforms placebo<\/h2>\n

There is always a concern with mental health medication that much of the supposed benefits come from a placebo effect \u2013 for instance, SSRIs, which are used to treat depression, were much more effective when they first came out in the 1980s than they are today.<\/p>\n

However, a public speaking study from 2011 concluded<\/a> that CBD can significantly reduce anxiety. Annoyingly, the research was largely forgotten at the time, when awareness surrounding CBD and medical cannabis in general was pretty poor. But this high-quality study, which was featured in the Neuropsychopharmacology <\/em>journal, is worth exploring in more depth.<\/p>\n

All of the participants had social anxiety, but none had tried treatment for condition \u2013 this made them more open and objective toward CBD than those who had experimented with anxiety medication. The study involved administering either a dose of CBD or a placebo to the volunteers and putting them through a simulated public speaking test.<\/p>\n

The results were staggering. The CBD helped participants to feel more confident in their speech, while reducing cognitive impairment and anticipatory speech alert. Anticipatory anxiety can have a detrimental impact on public speaking, causing nervousness before a speech which then spills over to effect performance. That CBD reduces anxiety in multiple areas is testament to how promising a treatment it is.<\/p>\n

Indeed, the research team concluded that CBD could be used to treat \u201canxiety behaviors\u201d in another disorders, including generalized anxiety, social anxiety and obsessive-compulsive disorder (OCD). Moreover, there were no side effects from CBD treatment that exacerbated anxious symptoms.<\/p>\n

Final thought<\/h2>\n

Anxiety affects people of all ages, and since many existing drugs such as benzodiazepines can be addictive and cause side effects such as insomnia, finding a non-aggressive form of treatment for the disorder in CBD is a massive breakthrough. The next step for researchers should be to study other non-psychoactive cannabinoids in-depth to see whether they can help too.<\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

 <\/p>\n

Disclosure:<\/strong>\u00a0This blog may contain affiliate links. If you make a purchase using one of these links, I may earn a small commission at no cost to you. All opinions are strictly those of the author and may not reflect the company or product that they are mentioning.
\nDisclaimer:<\/strong>\u00a0Sweet Honeybee Health, it’s owners and it’s featured authors are not medical professionals. Content on this website is intended for informational purposes only. Do not use the information you find on this site as medical advice. You are encouraged to seek the advice of a medical professional prior to trying any health remedy, no matter how safe or risk-free it may claim to be.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"

By a featured author from cbdvapejuice.net   Anxiety is an intensely irritating mental disorder that, if allowed to manifest, can have a debilitating effect on quality of life. Pernicious self-doubt creeps in and the stomach begins to turn, making the simplest of tasks a mighty ordeal as fears of embarrassment and humiliation kick in for no good reason. Anxiety can be a vicious circle \u2013 ceding to irrational worry often reinforces these doubts and, coupled with low self-esteem, we can end up becoming our own worst enemy. How can we go about life when we are constantly battling against ourselves? Thankfully, non-psychoactive cannabis, namely cannabidiol (CBD), is coming to the rescue of many anxiety patients around the world, many of whom consume the compound as part of a CBD vape oil. This compound, which researchers have paid increasing interest to since the turn of the century, boasts anti-anxiety and antidepressant properties, which have been scientifically proven in both animal models and humans. CBD is a non-aggressive form of treatment, \u2013 the absence of tetrahydrocannabinol (THC) means there\u2019s no psychotropic side effects (i.e. getting high), and nor will CBD e-liquid\u00a0have a numbing effect on your personality, as some medication is known to do. But what makes CBD so effective against anxiety? To understand this, we must first get to grips with the mechanism that CBD \u2013 along with other cannabinoids \u2013 functions in: the endocannabinoid system. CBD and the endocannabinoid system In the early 1990s, researchers stumbled across a previously unknown network of neurotransmitters and receptors, which were found to hold influence over many physical and mental variables. The system typically works with endogenously-produced chemicals known as endocannabinoids, however, cannabinoids from cannabis are effective substitutes. For example, psychoactive THC bears many molecular similarities to anandamide, an important endocannabinoid which is a natural anti-depressant. Anandamide is called the \u2018human THC\u2019 or \u2018bliss molecule\u2019 by some and connects to CB1 receptors \u2013 these are highly-concentrated in the brain, which provides an explanation for THC\u2019s mind-altering effects. CBD also has an impact on anandamide, albeit a slightly more nuanced one. Instead of replacing the endocannabinoid, CBD helps to boost anandamide in the body by stopping the fatty acid amide hydrolase (FAAH) enzyme from breaking it down. Increased levels of anandamide in the body is likely to improve mood. However, CBD\u2019s benefits do not stop there \u2013 for anxiety, specifically, the interactions the compound has with gamma-Aminobutyric acid (GABA) neurons appear key. GABA is a neurotransmitter that, when operating correctly, has a calming effect on neuronal activity \u2013 an over-excited brain can cause all kinds of problems, including insomnia, schizophrenia, epilepsy and anxiety. CBD has a modulating effect on GABA, but curiously does not bind directly to CB1 or CB2 receptors. However, scientists have a good idea on how CBD interacts with GABA \u2013 and therefore reduces anxiety \u2013 from the effects endocannabinoids have on the neurotransmitter. When required, neurons can synthesize anandamide and 2-AG \u2013 research has shown that these endocannabinoids can directly influence GABA receptors. Public speaking study shows CBD outperforms placebo There is always a concern with mental health medication that much of the supposed benefits come from a placebo effect \u2013 for instance, SSRIs, which are used to treat depression, were much more effective when they first came out in the 1980s than they are today. However, a public speaking study from 2011 concluded that CBD can significantly reduce anxiety. Annoyingly, the research was largely forgotten at the time, when awareness surrounding CBD and medical cannabis in general was pretty poor. But this high-quality study, which was featured in the Neuropsychopharmacology journal, is worth exploring in more depth. All of the participants had social anxiety, but none had tried treatment for condition \u2013 this made them more open and objective toward CBD than those who had experimented with anxiety medication. The study involved administering either a dose of CBD or a placebo to the volunteers and putting them through a simulated public speaking test. The results were staggering. The CBD helped participants to feel more confident in their speech, while reducing cognitive impairment and anticipatory speech alert. Anticipatory anxiety can have a detrimental impact on public speaking, causing nervousness before a speech which then spills over to effect performance. That CBD reduces anxiety in multiple areas is testament to how promising a treatment it is. Indeed, the research team concluded that CBD could be used to treat \u201canxiety behaviors\u201d in another disorders, including generalized anxiety, social anxiety and obsessive-compulsive disorder (OCD). Moreover, there were no side effects from CBD treatment that exacerbated anxious symptoms. Final thought Anxiety affects people of all ages, and since many existing drugs such as benzodiazepines can be addictive and cause side effects such as insomnia, finding a non-aggressive form of treatment for the disorder in CBD is a massive breakthrough. The next step for researchers should be to study other non-psychoactive cannabinoids in-depth to see whether they can help too.           Disclosure:\u00a0This blog may contain affiliate links. If you make a purchase using one of these links, I may earn a small commission at no cost to you. All opinions are strictly those of the author and may not reflect the company or product that they are mentioning. Disclaimer:\u00a0Sweet Honeybee Health, it’s owners and it’s featured authors are not medical professionals. Content on this website is intended for informational purposes only. Do not use the information you find on this site as medical advice. You are encouraged to seek the advice of a medical professional prior to trying any health remedy, no matter how safe or risk-free it may claim to be.<\/p>\n","protected":false},"author":1,"featured_media":340,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[42,4,44],"tags":[12,41,6,32,20,33,34,37,45,38,35,39,36,40,31],"class_list":["post-339","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anxiety","category-cbd-blog-posts","category-guest-blogger","tag-anxiety","tag-cannabinoid","tag-cbd","tag-cbd-e-liquid","tag-cbd-oil","tag-cbd-vape","tag-cbdvapejuice","tag-health","tag-hemplebox","tag-mental","tag-ocd","tag-physical","tag-placebo","tag-review","tag-thc"],"yoast_head":"\nWhat makes CBD so effective against anxiety? - Sweet Honeybee Health CBD<\/title>\n<meta name=\"description\" content=\"CBD product reviews and articles. 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